Jamie, a twenty-four-year-old who came to New York City to fulfill his dream of being a writer, now finds himself in a frightfully boring job in the "factual verification department" of Gotham Magazine under tight-lipped boss Clara. Jamie soon discovers the party-scene of New York where he meets characters like Tad, who brings Jamie into a world of cocaine, sex and all-night partying at the Odeon club. Jamie indulges but eventually finds himself spinning out of control. His wife Amanda, a model, leaves him to follow her dream in Paris. He loses touch with his brother, Michael, who is left confused and alone since the death of their mother, and Jamie loses his job.
Drugs and partying get the better of Jamie, as he starts to be haunted by hallucinations, while Chuck Bean, the number one reporter in town, worms his way into Jamie's brain. Jamie spirals out of control as the hallucinations and reality start to crumble.
Tad introduces Jamie to his cousin, Vicky. It is meant to be nothing but a one-night engagement, but Jamie finds himself drawn to the rationality, innocence and philosophical tendencies of Vicky. He soon decides to turn his life around, forgetting about Amanda, deserting Tad, reconnecting with Michael, being with Vicky and finally re-starting the novel he once gave up on.